Esophageal Cancer

HomeDigestive system diseasesEsophageal Cancer

Esophageal cancer is a disease characterized by the abnormal growth of cells in the lining of the esophagus, the muscular tube responsible for transporting food from the throat to the stomach. While relatively less common compared to other cancers, its aggressive nature underscores the importance of early detection and intervention.

Symptoms

Esophageal cancer often remains asymptomatic in its early stages, making it challenging to diagnose. However, as the disease progresses, individuals may experience:

Difficulty swallowing (dysphagia)
Persistent or worsening heartburn or indigestion
Unexplained weight loss
Chest pain or discomfort
Chronic cough or hoarseness
Vomiting or coughing up blood

Risk Factors

Several factors increase the risk of developing esophageal cancer, including:

Male Gender
Age over 50
Tobacco and Alcohol Use
Obesity
Chronic GERD
Family History

Screening and Diagnosis

Esophageal cancer screening aims to detect abnormalities in the esophageal lining before symptoms manifest fully. While routine screening is not recommended for the general population, individuals with certain risk factors, such as chronic GERD or a family history of esophageal cancer, may benefit from screening tests, including:

Upper Endoscopy

A procedure using a flexible tube with a camera to visualize the esophagus and obtain tissue samples for biopsy.

I would exclude this as we rarely If ever use barium swallows for cancer evaluation They are used in dysphagia or esophageal dysmotility workup.
Esophageal Biopsy

Tissue sampling to confirm cancerous changes and determine cancer stage.

Management

Treatment for esophageal cancer depends on various factors, including cancer stage, cancer type, overall health, and individual preferences. Options may include:

Surgery

Surgical removal of cancerous tissue, either through endoscopic resection or esophagectomy.

Chemotherapy

Systemic treatment using powerful drugs to kill cancer cells or shrink tumors.

Radiation Therapy

Targeted radiation to destroy cancer cells or alleviate symptoms.

Targeted Therapy

Drugs targeting specific cancer cell mechanisms to inhibit growth and spread.

Immunotherapy

Harnessing the body's immune system to recognize and attack cancer cells.